StatPlus will collaborate with investigators and clients in the protocol/CRF development to:

1. Develop protocol from scratch or refine the protocol template received from the client,Emphaome will

be in the issues of study design Endpoint selection,patient selection,trial duration,sample size

determination,and statistical analysis.The protocol will be local hospitals

• • • Meet the requirements of DOH and local hospitals

    • Serve marketing purpose

    • Demonstrate strong scientific base

    • Minimize cost

2. Design CRFs based on protocol to capture all necessary information specified by Protocol.

3. Design informed consent form